Course: MCB3025F

36 NQF credits at NQF level 7

Convener:
Dr R Hurdayal

Course entry requirements:
MCB2020F, MCB2021F and MCB2022S or MCB2023S

Course outline: 
This course addresses how modern techniques of structural and chemical biology are being used to solve biological problems. It draws on multiple aspects of macromolecular biochemistry including nucleic acid structure and interactions, signalling proteins and membrane proteins, and demonstrates how this knowledge can be used in drug discovery and protein design in biotechnology. Topics include: mechanisms of reversible and irreversible enzyme inhibitors, ligand binding, protein folding, molecular basis for protein function, regulation of protein activity, cell signalling and proteomics.

Lecture times:
Monday - Friday, 5th period

DP requirements:
50% average for assignments and practical reports; attendance at all practicals and tutorials.

Assessment:
Tests count 40%; practicals, tutorials essays and assignments count 10%; one 3-hour examination written in June counts 50%. A subminimum of 40% in the examination is required.